The amide bond can be activated for cleavage under mild, neutral conditions by chemical derivatization, a British group has demonstrated (Angew. Chem. Int. Ed., DOI: 10.1002/anie.201107117). Amide ...

Chemists at the University of Illinois, Urbana-Champaign, have identified a deoxyribozyme that catalyzes amide hydrolysis, the first step toward making a DNA-based enzyme that can cleave proteins in ...

In proteins, amino acids are held together by amide bonds. These bonds are long-lived and are robust against changes in temperature, acidity, or alkalinity. Certain medicines make use of reactions ...

This is a scheme of reaction rate acceleration of amide hydrolysis by inclusion in the self-assembled molecular cage. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news ...