Please provide your email address to receive an email when new articles are posted on . Central sensitization may be an important underlying factor that complicates the treatment of chronic pain and ...

The burden of chronic pain. Source: GoodIdeas / Shutterstock Nerve sensitization often contributes to chronic pain states, such as back pain, migraines, and irritable bowel. Sensitization is an ...

This blog post was written with contributions by Jamie Pribyl, DPT. Chronic pain is a condition in the nervous system where a light switch seemingly got turned on and never got turned off. Patients ...

This first-of-its-kind study by researchers at The Ohio State University Wexner Medical Center and College of Medicine and University of Michigan Medical School explored one potential mechanism – ...

Central sensitization describes the process by which neurons in the central nervous system become hyperresponsive following persistent or intense noxious input. This phenomenon relies on synaptic ...

Findings suggest that including slowly repeated evoked pain (SREP) in quantitative sensory testing protocols may enhance assessments of altered pain modulation in different pain conditions. Study ...

CLEVELAND, Ohio — Patients with fibromyalgia and those prone to opioid addiction may have something in common, researchers say: the part of the brain that controls the body’s perception of pain has ...

Discover how recent Bayesian network meta-analyses map the long-term efficacy thresholds of amitriptyline vs botulinum toxin ...

Pain sensitization has a major impact on the perception of pain, affecting both physical function and quality of life (QoL), in patients with knee osteoarthritis (OA), according to the results of a ...

Scientists have long noted a connection between opioid use disorder (OUD) and chronic pain, however brain mechanisms linking OUD and chronic pain are poorly understood. A new study has explored one ...