Centrosomes are not essential for cell division in most animal cells, although they contribute to the efficiency of mitotic spindle assembly. Centrosome loss is tolerated surprisingly well in fly ...

Planar cell polarity (PCP) signalling is a well-conserved developmental pathway regulating cellular orientation during development. An evolutionarily conserved pathway readout is not established and, ...

EPFL scientists discover that certain cell structures, the centrioles, could act as information carriers throughout cell generations. The discovery raises the possibility that transmission of ...

Centrioles are cylindrical structures involved in the generation of microtubules - fibers inside of cells that form a network to provide structure and shape to cells and to mediate transport processes ...

All life on earth depends upon the process of mitosis or cell division in which the chromosomal content of a cell is equally divided between two new cells. For mitosis to occur, the chromosomes in ...

How cell division occurs and is coordinated with organismal development is subject of intense research interest, as is how this process malfunctions in the development of tumors. Researchers have been ...

Centrioles are cylindrical structures involved in the generation of microtubules—fibers inside of cells that form a network to provide structure and shape to cells and to mediate transport processes.

Centrioles, the barrel-shaped organelles best known for their role in cell division, may also put their stamp on early embryos. In a newly fertilized embryo, the centrioles that are present come ...

The goal of my research is to understand the biogenesis of centrioles/centrosomes and primary cilia, and how defects in these processes affect mammalian cell physiology and evoke stress responses.