A new study indicates a common genetic variant may interact with gut bacteria to trigger chronic inflammation in ulcerative colitis. The findings may help explain why people experience the disease ...
Bacteria uses multiple defense mechanisms to survive in the host body. Shigella bacteria, that causes colitis, disable multiple host defense pathways using three specialized effector proteins, as ...
A toxin produced by bacteria found in dirty water kills off immune cells in the lining of the colon, meaning people whose guts are colonised by these bacteria are much more likely to develop a ...
Among those with ulcerative colitis, they found that smokers had certain bacteria usually found in the mouth, such as Streptococcus, growing in the gut, specifically in the colonic mucosa that cover ...
IBD involves chronic inflammation of the intestine that causes diarrhea, abdominal pain, and bloody stools. IBD comprises Crohn’s disease (CD) and ulcerative colitis (UC), both of which prevail ...
BERLIN — An individual’s profile of antibody responses to a range of herpes viruses and encapsulated bacteria such as Streptococcus could predict the onset of inflammatory bowel disease (IBD) up to 10 ...
Probiotics can help maintain a healthy gut microbiome or restore populations of 'good bacteria' after a heavy course of antibiotics. But now, they could also be used as an effective treatment strategy ...
Let’s break down the research.
The human gut is home to trillions of bacteria that play vital roles in digestion, immunity, and overall health. Disruption of the interaction between the gut microbiome and the host can contribute to ...
Researchers have identified a gut-genetic interaction that could trigger an overactive immune response in the colon — offering one possible explanation for the pain and bleeding of ulcerative colitis, ...
Diagram showing the mechanism discovered in the study. Inflammation of the intestines in ulcerative colitis results from an excessive helper Th2 immune response. Smoking leads to aromatic compounds ...