When people who use illegal drugs feel like they have to hide their use, the risk of overdose and death soars.

Dr. David Brendel answers the question: 'Substance Abuse And Depression?' — -- Question: What is the relationship between depression and substance abuse? Answer: There is a very close ...

By comparison, typically antidepressants like SSRIs work by slowly adjusting serotonin levels and often take weeks to show ...

Recreational ketamine use has increased in the United States in recent years, outpacing its rise as a treatment for depression, a new analysis suggests. The hallucinogenic drug — a controlled ...

More than 200 commonly prescribed drugs could have that side effect. More than one-third of American adults may be using prescription medications that can potentially cause depression or increase the ...

“You may feel like you’re going to die — but you’re not. Your body is right here in this safe place and we are monitoring you to ensure you are safe.” That’s what Steph Mahrle, a 43-year-old ...

Addiction changes the brain, body, and behavior. Persistent insomnia, craving, depression, anhedonia, and anxiety may continue for months after sobriety, often leading to relapse. While we search for ...

But when the researchers analyzed the data, they found that fluoxetine appeared not to provide meaningful benefits for ...

Similarly, in a warning about compounded finasteride, the United States Food and Drug Administration stated in April 2025 ...

A new study has found that antidepressant resistance is more common than was thought: 48% of people with depression have tried at least two medications without effect, while 37% have tried four or ...

The U.S. Food and Drug Administration has approved the expanded use of Johnson & Johnson's drug Caplyta as an add-on treatment for adults with major depressive disorder, the company said on Thursday.