Figure 1: The amn locus harbors a small DNA deletion. Figure 3: Identification of an Amn candidate that is disrupted and partially deleted by the transgene insertion. Figure 4: Targeted deletion of ...

An unexpectedly versatile and regenerative stem cell in early embryos may be key to creating new effective fertility treatments, suggests a new study in mice from the University of Copenhagen. It ...

The endoderm is the innermost layer of cells in very early vertebrate and insect embryos. It is one of the three primary germ cell layers and gives rise to epithelial tissue lining some organs, ...

An unexpectedly versatile and regenerative stem cell in early embryos may be key to creating new effective fertility treatments, suggests a new study in mice from the University of Copenhagen. The ...

Pluripotent stem cells, created from human skin or mouse ear tissue, are shown here becoming endoderm cells. The endoderm is one of the three primary germ layers that ultimately contribute to the ...

How did the gut, the skin and musculature evolve? This question concerns scientists for more than a century. Through the investigation of the embryonic development of sea anemones, a very old animal ...

Interim results from a multicenter clinical trial demonstrate insulin secretion from engrafted cells in patients with type 1 diabetes. The safety, tolerability, and efficacy of the implants, which ...

Diabetes. 2013;62(10):3514-3522. In summary, our data do not support an early phase of endocrine differentiation in human embryos analogous to primary transition during mouse development, and we did ...

For the first time, scientists have derived insulin-secreting pancreatic endoderm cells from human pluripotent stem cells (PSCs), grafted these cells into 26 patients with type 1 diabetes, and ...

Imagine if you could repair damaged tissue in your organs. That is what stem cell research is working towards, because stem cells have tremendous potential to produce the cells of organs such as the ...