With a length of around eight meters and its countless finger-shaped protrusions, known as villi, the intestine represents the largest contact surface in the inner of our body that comes in contact ...

A research team led by scientists from the State University of Campinas (UNICAMP) in São Paulo, Brazil, has made significant progress in understanding the relationship between gut microbiota and ...

Disruption of the intestinal epithelial barrier is a hallmark of Inflammatory Bowel Disease (IBD), yet mechanisms of epithelial repair remain poorly understood. We developed a scalable human colon ...

A review integrates murine, human, and bovine evidence on epithelial and mesenchymal stem cells in the mammary gland, ...

Normal epithelial cells show the ability to push out precancerous ones present in the epithelium, by means of 'cell competition.' But the exact molecular mechanism of this recognition by normal ...

Crypt-base-columnar cells are continuously dividing intestinal stem cells that generate IECs, which are composed by distinct specialised cell types that play different functions: Enterocytes (in the ...

Researchers at Queen Mary University of London and University of Cambridge in collaboration with colleagues at HHMI Janelia and NIH, have created some of the most detailed three-dimensional maps ever ...

The small airways serve as a primary line of defense against inhaled particles and facilitate gas exchange by directing air to the alveoli. These small airways are critical in the pathophysiology of ...

Deep in the folds of the intestine, in microscopic pockets called crypts, a quiet surveillance system is always at work. Stem cells lining the gut wall are not just rebuilding tissue—they are ...

A 2026 review finds that iPSC-derived retinal pigment epithelium shows mechanistic promise for defined retinal-toxicity ...