This review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), shedding light on potential therapeutic targets for combating tumor progression, ...

HMGA2 is a non-histone chromatin-binding protein that has emerged as a critical regulator in both cancer progression and stem cell biology. Frequently overexpressed in various malignancies, HMGA2 ...

Scientists at University of California, San Diego (UCSD), have developed a new approach to destroying cancer stem cells (CSCs)—the hard-to-find cells that help cancers spread, come back after ...

As cell therapy advances toward clinical reality, iPSC-derived cellular products, in vivo reprogramming strategies, and ...

Scientists at University of California San Diego have developed a new approach to destroying cancer stem cells – hard-to-find cells that help cancers spread, come back after treatment and resist ...

Researchers from University of California San Diego Sanford Stem Cell Institute have discovered that spaceflight accelerates the aging of human hematopoietic stem and progenitor cells (HSPCs), which ...

In a first-of-its-kind clinical trial, UCLA scientists have shown it's possible to reprogram a patient's blood-forming stem cells to generate a continuous supply of functional T cells, the immune ...

UCLA and Stanford Medicine researchers, in collaboration with scientists from the University of Utah and Columbia University, ...

Last year, more than 70,000 people in the United States were diagnosed with head and neck cancers, and its rates have steadily risen worldwide. These cancers arise from squamous epithelial cells ...

The current path to CAR-T cell therapy is, by any measure, a logistical ordeal. A patient’s immune cells must be drawn out of ...

Swallowing is a fundamental human function that supports nutrition and communication. Damage to swallowing muscles can reduce ...