A Japanese research team has uncovered how sugar chains (glycans) modifications dynamically regulate the structure and function of human immunoglobulin G (IgG) antibodies. By integrating nuclear ...
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Lower IgG hinge controls antibody assembly and immune function
The lower hinge of immunoglobulin G (IgG), an overlooked part of the antibody, acts as a structural and functional control ...
New findings from a Phase II study indicate that antenatal treatment with the FcRn blocker nipocalimab resulted in low fetal drug exposure and transient reductions in infant IgG levels at birth, ...
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