The itching, redness and swelling of an allergic reaction are caused by mast cells—the vigilant first responders of the immune system that spring into action with histamine-filled granules in response ...

Food allergy, or the aggressive immune system reaction following the consumption of a certain food or food ingredient, typically involves immunoglobulin E (IgE) antibodies and can be potentially ...

Millions of people who recover from the initial stages of COVID-19 continue to suffer from lingering nerve pain, fatigue, and cognitive issues. A new academic review proposes that a specific type of ...

Depending on one's perspective, "mast cell activation syndrome (MCAS)" is either a relatively rare, narrowly defined severe allergic condition or a vastly under-recognized underlying cause of multiple ...

According to an international multicenter study, CD2-negative mast cells are associated with significantly reduced overall survival in patients with SM. Patients with CD2-negative mast cells have ...