Every cell in the body has the same DNA, but different cell types—such as muscle or brain cells—use different parts of it.

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

Duchenne muscular dystrophy (DMD) is a rare but devastating genetic disorder that causes muscle loss and physical impairments. Researchers have shown in a mouse study that the powerful gene editing ...

Michael Gotthardt at the Max Delbrück Center and collaborators are developing a drug to treat a common type of heart failure characterized by impaired cardiac filling. In a recent study, his group and ...