Intracellular peptides, generated predominantly via the ubiquitin–proteasome system, have emerged as critical modulators of cell signalling. These peptides play multifaceted roles, ranging from ...

Avoid common mistakes in multiplexing protein secretion assays. Discover best practices to ensure accurate results.

Heterotrimeric G proteins, comprising Gα, Gβ and Gγ subunits, are central to the transduction of extracellular signals into precise intracellular responses in plants. These proteins not only regulate ...

Artificial intelligence (AI) is transforming how scientists understand proteins—these are working molecules that drive nearly every process in the human body, from cell growth and immune defense to ...

Scientists have uncovered a direct molecular mechanism by which gut bacteria inject proteins into human cells, reshaping immune responses and potentially driving inflammatory disease. Scientists have ...

The recent discovery of glycoRNAs on the cell surface upended the world of cell biology. These glycoRNAs were found to form highly organized clusters with cell surface RNA binding proteins (csRBPs), ...

Age-related changes in protein tagging and degradation may help explain how the brain declines over time and why diet can still influence these processes.

Targeting OTULIN has proven to eliminate toxic tau proteins in human neurons for the first time, opening a new avenue for treating dementia.

Liver cancer is one of the three deadliest cancers worldwide, and metabolic dysfunction-related cases have become ...

In Alzheimer’s disease and other dementias, a protein called tau can pile up inside brain cells and form toxic clumps. Those clumps help drive memory loss and other symptoms.

Liver cancer is one of the three deadliest cancers worldwide, and metabolic dysfunction-related cases have become ...