Researchers at the MRC Laboratory of Medical Sciences (LMS) and collaborators have uncovered one of the earliest steps in DNA replication: the moment a cell first opens its DNA to begin making a copy ...
Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such structure, the G-quadruplex (G4), looks like a knot. These knots can play ...
The NIH 4D Nucleome consortium, of which this study is a part, aims to extend this kind of mapping into the fourth dimension: ...
7don MSN
Two ways to read a genome: Body-wide, single-cell atlas maps DNA folding and methylation together
Every cell in the human body carries the same 3 billion letters of DNA, yet a neuron, a heart muscle cell and a pancreatic beta cell each use that shared code to do entirely different jobs. How cells ...
New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...
DNA's iconic double helix does more than "just" store genetic information. Under certain conditions, it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...
But when the DNA doesn't fold the right way, it can disrupt normal cell functions and lead to serious diseases, including cancer. Historically, scientists have relied on data that averaged results ...
Researchers at Genentech Inc. and UC Davis have worked out the structure of the RAD51 complex, which repairs breaks in DNA. When DNA experiences a double-strand break, enzymes trim back one of the two ...
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