Medically intractable complex partial seizures can be cured or improved using surgery, but accurate preoperative localization of the seizure focus is essential for complete seizure control.

The 18-kDa translocator protein (TSPO) is expressed within microglia and macrophages and has been used as a target for PET ligands to study disease processes that involve microglial activation or the ...

The recently released Biograph mMR is the first commercially available integrated whole-body PET/MR scanner. There are considerable advantages to integrating both modalities in a single scanner that ...

Radioimmunotherapy and nuclear imaging (immuno-PET/SPECT) of cancer with radiometal-labeled antibody fragments or peptides is hampered by low tumor-to-kidney ratios because of high renal radiometal ...

Journal of Nuclear Medicine September 2026, jnumed.126.272814; DOI: https://doi.org/10.2967/jnumed.126.272814 ...

PET/CT imaging of cancer with combined PET and CT scanners has become a standard component of diagnosis and staging in oncology (1,2). The glucose analog 18 F-FDG has been shown to concentrate in ...

The subjects of this study were those who underwent conventional wbPET imaging for clinical examination, for free medical treatment, or as part of the Japan Agency for Medical Research and Development ...

The translocator protein (TSPO) is expressed at low levels in the healthy human brain and is markedly upregulated in response to brain injury and inflammation. This increase in TSPO expression is ...

TheraPb Phase 1b: First-in-Human Dose-Escalation and Optimization Study of 212 Pb-ADVC001 in PSMA-Positive Metastatic Androgen Pathway Modulation–Resistant Prostate Cancer ...

Affibody molecules constitute a new class of probes for radionuclide tumor targeting. The small size of Affibody molecules is favorable for rapid localization in tumors and clearance from circulation.

The use of synaptic vesicle glycoprotein 2A radiotracers with PET imaging could provide a way to measure synaptic density quantitatively in living humans. 11C-UCB-J (( R ...

Absolute myocardial blood flow (MBF) and myocardial flow reserve (MFR) provide incremental diagnostic and prognostic information over relative perfusion alone. Recent development of dedicated cardiac ...