WHY IS FAP-TARGETED THERAPY ATTRACTIVE? FAP-positive CAFs are found in more than 90% of epithelial cancers, therefore representing a potential pan-cancer target (6). Targeting FAP to deplete stromal ...
Journal of Nuclear Medicine September 2026, jnumed.126.272814; DOI: https://doi.org/10.2967/jnumed.126.272814 ...
PET/CT imaging of cancer with combined PET and CT scanners has become a standard component of diagnosis and staging in oncology (1,2). The glucose analog 18 F-FDG has been shown to concentrate in ...
The subjects of this study were those who underwent conventional wbPET imaging for clinical examination, for free medical treatment, or as part of the Japan Agency for Medical Research and Development ...
Introduction: Per the 2023 American Society of Nuclear Cardiology (ASNC) recommendations, SPECT/CT should be done with CT attenuation correction (AC) and every effort should be made to acquire ...
TheraPb Phase 1b: First-in-Human Dose-Escalation and Optimization Study of 212 Pb-ADVC001 in PSMA-Positive Metastatic Androgen Pathway Modulation–Resistant Prostate Cancer ...
Introduction: Yttrium-90 (Y90) is an efficient therapeutic radioisotope for tumour treatment due to its high-energy beta rays. However, due to the vast energy spectra of Y-90, its always been ...
Multisystemic inflammation might be a key pathophysiologic mechanism in post–coronavirus disease 2019 (post-COVID) syndrome. N,N- diethyl-2-(2-(4-(2-fluoroethoxy)phenyl)5,7dimethylpyrazolo[1,5a] ...
In recent years, several radiotracers targeting the prostate-specific membrane antigen (PSMA) have been introduced. Some of them have had a high clinical impact on the treatment of patients with ...
Journal of Nuclear Medicine June 2025, 66 (supplement 1) 252173; ...
Treatment-induced neuroendocrine prostate cancer (NEPC) is a lethal subtype of castration-resistant prostate cancer. Using the 89Zr-labeled delta-like ligand 3 (DLL3) targeting antibody SC16 ...
The use of synaptic vesicle glycoprotein 2A radiotracers with PET imaging could provide a way to measure synaptic density quantitatively in living humans. 11C-UCB-J (( R ...
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