Glendale, AZ -- The 49ers just blew out the Arizona Cardinals 41-22. Granted, the Cardinals got blown out last week too and ...

An injured Kyler Murray, a depleted backfield and really, inconsistent football. It didn’t stop today either in their loss to ...

The San Francisco 49ers picked off Arizona's Jacoby Brissett twice, a defensive counter to the QB's NFL record 47 completions ...

I don’t know any other running backs that can do that, to be honest,” Brock Purdy said of Christian McCaffrey’s touchdown ...

Brock Purdy returned from a six-game absence to throw three touchdowns as the 49ers (7-4) romped to a 41-22 win over the host ...

San Francisco 49ers QB Brock Purdy dispensed with questions over his health and simultaneously silenced debate over Mac Jones ...

After a frustrating six-week wait to return from injury, 49ers quarterback Brock Purdy didn't take long to get back into a ...

Head coach Kyle Shanahan of the San Francisco 49ers looks on during warmups before the game against the Arizona Cardinals at ...

The San Francisco 49ers had huge plays on both sides of the ball to earn a blowout win over the Arizona Cardinals. Here are ...

Kyle Madson of Niners Wire takes Cardinals fans behind enemy lines before the Week 11 Cardinals vs. 49ers showdown.

Arizona had the passing game working, but it didn't matter in a 41-22 loss to San Francisco at State Farm Stadium in Glendale ...

Brock Purdy passed for 200 yards and three touchdowns in his first game since Sept. 28, Christian McCaffrey scored three ...