McCaffrey is not in line to play in Saturday's preseason opener against the Broncos, Eric Branch of the San Francisco Chronicle and David Lombardi of SFStandard.com report. With Isaac Guerendo ...

Two top contenders this year face off in the preseason opener, with the San Francisco 49ers hosting the Denver Broncos. However, many fans are wondering whether stars Christian McCaffrey and Bo Nix ...

The San Francisco 49ers added some running back depth to their roster ahead of their preseason opener vs. the Denver Broncos.

Ahead of the Denver Broncos ' preseason game against the San Francisco 49ers tonight, we asked Kyle Madson of Niners Wire ...

The 49ers scored a touchdown on their opening series of the preseason, then their defense crumbled by halftime against the ...

The Denver Broncos and the San Francisco 49ers will kick off their 2025 preseason at Levi's Stadium on Saturday.

The San Francisco 49ers preseason slate opens Saturday evening against the Denver Broncos at Levi's Stadium.

Purdy didn't warm up and isn't likely to play in Saturday's preseason game against Denver, Nick Wagoner of ESPN.com reports. Purdy is among a slew of 49ers healthy regulars, including Christian ...

The San Francisco 49ers signed running back Ke’Shawn Vaughn to a one-year deal ahead of their first preseason game against the Denver Broncos. Vaughn signed with the 49ers’ practice squad in August ...

The 49ers won't play their starters in their preseason debut against the Denver Broncos, but these 11 players will be worth ...

Nearly 40 players are brand new to the 49ers’ roster and poised to make their debut in Saturday’s preseason opener against ...

San Francisco 49ers head coach Kyle Shanahan prides himself on his play-calling prowess. Shanahan announced he'll allow ...