The endocannabinoid system is found throughout the brain and body and plays a key role in everything from memory and learning ...

NANOG has multifaceted roles in naïve hESCs, orchestrating transcriptional, metabolic, and epigenetic signatures in naïve hESCs, and governing acetyl-CoA synthesis, bivalent metabolism, and redox ...

Inhibitory receptors have increasingly been recognized as critical players in the maintenance of immune homeostasis. These receptors, expressed on a variety ...

Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial ...

The field of tissue-immune interactions has undergone significant transformation as emerging evidence demonstrates the centrality of local microenvironments ...

The endocrine system plays a crucial role in regulating physiological processes and maintaining homeostasis. While previous ...

Background Eosinophilic oesophagitis (EoE) is a chronic allergic disease characterised by oesophageal epithelial remodelling, barrier dysfunction and inflammation. The transcription factor forkhead ...

What are the physics of life? That is more than just a philosophical question—it has practical implications for our search ...

Opportunities in the TL1A and DR3 therapeutics market include developing novel immunotherapies for inflammatory bowel disease, leveraging increasing interest from major pharmaceutical firms. A focus ...

Northwestern Medicine scientists have identified previously unknown genetic mechanisms that promote antimicrobial resistance ...