Nature

A comparison of molecular and cytogenetic techniques for the diagnosis of pregnancy loss

Purpose: To evaluate the sensitivity, specificity, advantages, and limitations of multiplex ligation-dependent probe amplification compared with conventional karyotype analysis in the investigation of ...
Nature

MS-MLPA: an attractive alternative laboratory assay for robust, reliable, and semiquantitative detection of MGMT promoter hypermethylation in gliomas

Expression of the DNA repair protein O6-alkylguanine-DNA-alkyltransferase (AGT), encoded by the O6-methylguanine (O6-mG) -DNA-methyltransferase (MGMT) DNA repair gene, results in resistance to ...
Science Daily

Cheap, simple, noninvasive blood test may replace invasive diagnostic techniques in early pregnancy

Researchers in the Netherlands believe they are on the verge of developing a simple, prenatal blood test that would be able to detect accurately chromosomal abnormalities in the developing fetus. At ...
GEN

Existing Technique Can Detect Fetal Genetic Abnormalities in Maternal Blood

Team found that MLPA assay can identify fetal DNA without invasive sampling. Netherlands-based researchers suggest that a technique currently used to detect fetal chromosomal abnormalities in maternal ...
ascopubs.org

Comprehensive germline sequencing and MLPA analysis in breast cancer patients: 4 years of experience from an Indian cancer institute.

Effect of body mass index on the prognostic impact of progesterone receptor in postmenopausal ER+HER2- breast cancer: A nationwide study in Korean Breast Cancer Society and multi-institutional cohort.