New anti-HSV drug Pritelivir receives FDA approval: An 'oral treatment' option for existing drug-resistant herpes; note the differences in development and marketing c…

The target population is adult immunocompromised patients with HSV mucocutaneous lesions that are refractory to treatment ...
BIOENGINEER

New Loop-Tracing Algorithm Speeds Up Optimal Solutions to Transportation Problems

A new algorithm refines classical loop tracing in transportation simplex methods, matching optimal solutions while cutting ...
science

Evidence of active whole-genome doubling (WGD) subclones in non-WGD tumors

The pattern was previously used to classify WGD status for bulk samples (15, 26). Accordingly, we identified 27,484 WGD cells and 12,550 nWGD cells (Materials and Methods). The median ploidy of WGD ...
Archaeology

solution phase peptide synthesis comparison is mainly used for the synthesis of short peptides

In the realm of chemical laboratories and research, the methodology selected for creating sequences is paramount. When evaluating a solution phase peptide synthesis comparison, it is essential to ...
WKOW

SKYRIZI® (risankizumab) and RINVOQ® (upadacitinib) Data Highlight Long-Term Clinical and Endoscopic Outcomes Across Inflammatory Bowel Disease (IBD) at UEGW 2026

AbbVie's leadership in Inflammatory Bowel Disease (IBD) research programsLatest long-term and real-world data with SKYRIZI®(risankizumab) and RINVOQ® (upadacitinib) provide additional insight into cli ...
The Lancet

Retatrutide in adults with obesity and type 2 diabetes (TRIUMPH-2): a double-blind, parallel-group, randomised, placebo-controlled, phase 3 trial

dAustralian Centre for Accelerating Diabetes Innovations and Department of Medicine, Melbourne Medical School, The University of Melbourne, Melbourne, VIC, Australia eCentre for Research and Education ...