Background Quadriceps maximal voluntary contraction (QMVC) reliably measures quadriceps muscle force and predicts mortality in chronic obstructive pulmonary disease (COPD). However, the minimal ...

Pulmonary Rehabilitation Research Group, Department of Respiratory Medicine and Thoracic Surgery, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, UK Background: The ...

Department of Epidemiology and Public Health, University College London, London, UK Dr M Thomas, Department of General Practice and Primary Care, University of Aberdeen, Foresterhill Health Centre, ...

Background The EQ-5D, a generic health status questionnaire that is widely used in health economic evaluation, was recently expanded to the EQ-5D-5L to address criticisms of unresponsiveness and ...

Data on asthma treatment outcomes in Africa are limited. 449 patients with asthma (age 5–93 years) in Uganda were followed up for 2 years to determine rates of exacerbations and mortality and ...

Reduction of the risk of asthma attacks is a major goal of current asthma management. We propose to derive a risk scale predicting asthma attacks based on the blood eosinophil count and exhaled nitric ...

Introduction Cigarette Smoking is the leading cause of COPD; smoking cessation in COPD reduces mortality and is the only intervention proven to reduce the rate of FEV1 decline. Stop Smoking Services ...

Antileukotriene drugs are new therapeutic agents that have recently been approved for the treatment of asthma. Several cases of eosinophilic conditions including Churg-Strauss syndrome have been ...

Background Ambient fine particulate matter with aerodynamic diameter less than 2.5 µm (PM2.5) has been associated with deteriorated respiratory health, but evidence on particles in smaller sizes and ...

Introduction and Aim The efficacy and safety of nintedanib in patients with IPF were assessed in two replicate Phase III placebo-controlled INPULSIS trials. In both trials, nintedanib reduced disease ...

Background Patients with chronic obstructive pulmonary disease (COPD) are at increased risk of cardiovascular disease (CVD). The extent to which the excess CVD risk is captured by risk factors in ...

Correspondence to Dr Mitesh Patel, Medical Research Institute of New Zealand, Private Bag 7902, Wellington 6242, New Zealand; Mitesh.Patel{at}mrinz.ac.nz JP: A 25-year-old gentleman with asthma ...