Researchers from The University of Osaka find that mitochondria in macrophages can be degraded through the lesser-known path of microautophagy Macrophages are part of the immune system's frontline; ...

Macrophages are part of the immune system's frontline; they attack and "eat" invaders to protect surrounding cells. They, along with other cells, maintain intracellular conditions through ...

Macroautophagy has been extensively studied, but microautophagy is not understood as extensively. We found that this process seems to play a more prominent role than macroautophagy, at least in ...

Osaka, Japan – Macrophages are part of the immune system’s frontline; they attack and eat invaders to protect surrounding cells. They, along with other cells, maintain intracellular conditions through ...

美国国立卫生研究院叶一泓团队发现了CHIP保护溶酶体免受CLN4突变体诱导的膜损伤。2025年8月25日，国际知名学术期刊《自然—细胞生物学》发表了这一成果。 在这里，课题组生成并表征了诱导多 ...

Coronary microembolization (CME) occurs in patients with acute coronary syndrome and is caused primarily by atherosclerotic plaque rupture associated with surgery. CME can lead to arrhythmias, ...

Have you ever wondered how your body cleanses itself of damaged cells and rejuvenates? The answer lies in a remarkable process known as autophagy, a natural mechanism that plays a crucial role in ...

Recent research identifies microautophagy and key proteins, STK38 and GABARAPs, as essential for repairing damaged lysosomes, providing insight into cellular aging and potential treatments for ...

Researchers from Osaka University have shown for the first time that damaged lysosomes are repaired by a process called microautophagy, which is essential for preventing aging To age or not to age!

Researchers have shown that lysosomes, key organelles for maintaining cellular stability, can be repaired once damaged by a process termed microautophagy. They identified molecules called STK38 and ...

To age or not to age! How does aging affect organisms on a cellular level? What mechanisms help cells survive self-inflicted or external harm? It is known that lysosomes - critically important ...

Newswise — Osaka, Japan – To age or not to age! How does aging affect organisms on a cellular level? What mechanisms help cells survive self-inflicted or external harm? It is known that ...