In a large retrospective study, those taking a glucagon-like peptide 1 (GLP-1) receptor agonist drug were 36% less likely to develop colorectal cancer than those taking aspirin. Although the benefit ...
ActA mediates cross-talk between breast cancer cells and cancer-associated fibroblasts in the lung metastatic niche that enhances fibrosis and metastasis, implicating ActA as a potential therapeutic ...
Mesothelin secretion by cancer cells supports pancreatic cancer metastasis by inducing macrophage secretion of VEGFA and S100A9 to support cancer cell proliferation and survival, recruit neutrophils, ...
1Pancreas Center, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, State Key Laboratory of Druggability Evaluation and Systematic Translational ...
2Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Illinois. 3Robert H. Lurie Comprehensive Cancer Center ...
In MTAP-deficient cancer cells, PRMT5 expression and activity is preferentially required for cell growth. Major finding: In MTAP-deficient cancer cells, PRMT5 expression and activity is preferentially ...
1Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California. 2Cancer Institute, Stanford University School of Medicine, Stanford, ...
Institute of TCM-X/MOE Key Laboratory of Bioinformatics, Bioinformatics Division, BNRist/Department of Automation, Tsinghua University, Beijing, China.
1Department of Cell Growth and Tumor Regulation, Proteo-Science Center, Ehime University, Toon, Japan. Search for other works by this author on: 2Laboratory of Molecular Pharmacology & Developmental ...
The discovery and characterization of novel WRN helicase inhibitors provides pharmacological validation for the clinical development of WRN inhibitors for the treatment of patients with MSI tumors.
Cancer Res (2023) 83 (8_Supplement): LB031.
Abstract. Binding of steroid hormones to their cognate receptors regulates the growth of most prostate and breast cancers. We hypothesized that CYP11A inhibition might halt the synthesis of all ...
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