AbstractIntroduction:. Ikaros family zinc finger protein 1 and 3 (IKZF1/3) are essential transcription factors (TF) for the differentiation of B and T lymphocytes. IMiDs (e.g. pomalidomide, CC-220, CC ...
Integrative genetic analyses and functional studies in extranodal NK/T-cell lymphoma identify frequent disruptions of X-linked drivers, reveal prognostic molecular subgroups, and uncover recurrent MSN ...
ActA mediates cross-talk between breast cancer cells and cancer-associated fibroblasts in the lung metastatic niche that enhances fibrosis and metastasis, implicating ActA as a potential therapeutic ...
Cancer Res (2023) 83 (8_Supplement): LB329. Methods: Cellular potency of ABSK021 was evaluated by Celltiter-Glo assay in osteosarcoma cell lines and CSF-1R expression was evaluated by western blot. In ...
Mesothelin secretion by cancer cells supports pancreatic cancer metastasis by inducing macrophage secretion of VEGFA and S100A9 to support cancer cell proliferation and survival, recruit neutrophils, ...
1Pancreas Center, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, State Key Laboratory of Druggability Evaluation and Systematic Translational ...
In MTAP-deficient cancer cells, PRMT5 expression and activity is preferentially required for cell growth. Major finding: In MTAP-deficient cancer cells, PRMT5 expression and activity is preferentially ...
Abstract. AZD9833 is a potent, orally delivered, non-steroidal selective estrogen receptor degrader (SERD) that both antagonizes and degrades ERα. It is currently in clinical testing for the treatment ...
1Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California. 2Cancer Institute, Stanford University School of Medicine, Stanford, ...
3Department of Biology, Stanford University, Stanford, California. 5Cancer Biology Program, Stanford University School of Medicine, Stanford, California. 12Chan Zuckerberg Biohub, San Francisco, ...
Cancer Discov (2026) 16 (1): OF1.
1Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany. 2University of Tübingen, Tübingen, Germany.
Results that may be inaccessible to you are currently showing.
Hide inaccessible results
Feedback