Objective Live biotherapeutic products (LBPs) are biological products composed of living micro-organisms, developed to ...

Over the past few decades, the prevalence of chronic inflammatory and metabolic diseases has risen sharply, coinciding with significant environmental and lifestyle changes. While genetics play a role, ...

1 Department of Gastroenterology, The Second Hospital of Hebei Medical University, Hebei Key Laboratory of Gastroenterology, Hebei Institute of Gastroenterology, Hebei Clinical Research Center for ...

Non-alcoholic fatty liver disease (NAFLD) has rapidly become the most common chronic liver disease globally and is currently estimated to affect up to 38% of the global adult population. NAFLD is a ...

Objective Early-onset colorectal cancer (CRC) is increasing in the USA despite rapid declines in older ages. Similar patterns are reported in Australia and Canada, but a comprehensive global analysis ...

Introduction The Joint Advisory Group (JAG) ISREE initiative in 2019 called for an improvement of safety in endoscopy, one of the recommendations was simulation training for staff. Endoscopy ...

Objective A healthy lifestyle is the first-line treatment in non-alcoholic fatty liver disease (NAFLD), but specific dietary recommendations are lacking. Therefore, we aimed to determine whether ...

Correspondence to Professor Michelangelo Foti, Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva 1205, Switzerland; michelangelo.foti{at}unige.ch ...

Correspondence to Dr Citadel J Cabasag, Cancer Surveillance Branch, International Agency for Research on Cancer, Lyon, France; cabasagc{at}fellows.iarc.fr We read with interest the commentary by ...

Objective Artificial intelligence (AI) may reduce underdiagnosed or overlooked upper GI (UGI) neoplastic and preneoplastic conditions, due to subtle appearance and low disease prevalence. Only disease ...

Objective Autophagy participates in the progression of hepatocellular carcinoma (HCC) and the resistance of HCC cells to sorafenib. We investigated the feasibility of sensitising HCC cells to ...

Background Therapeutic antibodies (Abs) against the immune checkpoint ‘programmed cell death 1’ (PD1) achieve clinical benefit only in a small subset of patients with microsatellite instable (MSI+), ...