Introduction Preterm-born infants are particularly vulnerable to poor air quality, which may contribute to respiratory ...

Low-dose CT screening reduces lung cancer mortality,1 2 and the policy debate has moved beyond whether screening works to how programmes should be designed. Risk-based eligibility is central to that ...

Risk assessment in chronic obstructive pulmonary disease (COPD) still depends heavily on a familiar clinical shortcut: a ...

Background Antibiotic therapy before presentation (prior antibiotic exposure, PAE) is reported in 11–39% of patients with ...

Diarrhoea is the primary cause of nintedanib discontinuation in idiopathic pulmonary fibrosis. We investigated predictors in 100 prospective patients; 46% experienced diarrhoea, defined as common ...

Introduction Acetazolamide improves sleep apnoea in people living at low altitude and newcomers ascending to high altitude.

Systemic sclerosis (SSc) is a systemic autoimmune disease characterised by immune dysregulation and multiorgan fibrosis. 1 ...

Background Pulmonary rehabilitation (PR) is the cornerstone of non-pharmacological treatment for chronic obstructive pulmonary disease (COPD), yet fatigue often persists despite rehabilitation. We ...

Introduction Most research on idiopathic pulmonary fibrosis (IPF) has focused on the interplay among fibroblasts, the immune system and epithelial cells. There is growing evidence that microvascular ...

Background In most chronic airway diseases, identifying phenotypes has advanced clinical practice and research. However, no such phenotypes exist for paediatric bronchiectasis. We therefore sought to ...

A 65-year-old male, who does not smoke, with a history of right lower lobectomy for carcinoid tumour 15 years prior, was referred for persistent, unexplained cough over 12 months. This was ...

Background Disease modifying therapies for progressive fibrotic interstitial lung diseases (F-ILDs) slow physiological decline but have not consistently shown to improve patient-reported symptoms or ...