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Moreover, the soluble form has also been proposed as a biomarker for type I diabetes and even as a prognostic marker in tuberculosis and cancer [45, 46].

https://doi.org/10.1186/s40364-025-00771-5 Biomarker Research REVIEW Open Access

https://doi.org/10.1186/s40364-025-00783-1 Biomarker Research REVIEW Open Access

By leveraging routine epidemiological and blood biomarker data, PRIME enables the identification of high-risk individuals, facilitating targeted screening and early cancer detection.

The Author(s) 2025. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction …

These findings indicate that the expression of NINJ2 as a surface protein can be used as a novel biomarker for acquired ECF resistance in both intestinal and difuse gastric cancer cells.

While microfluidic platforms are powerful tools for biomarker analysis, accurate cancer diagnosis frequently requires the combined analysis of multiple biomarkers approach to improve …

Herein, we review the pathophysiology of CRS and neurotoxicity, and summarize the progress of predictive biomarkers to improve CAR-T cell therapy in cancer. Keywords: Chimeric antigen …

Furthermore, high expression of LAG-3 in TILs has been found to be significantly associated with a poor prognosis for immunotherapy in patients with HCC and, therefore, has the potential to …