Transplanted Islet Cells Survive Without Immune Suppression
Aug 5, 2025 · In a first for type 1 diabetes, researchers have gene-edited donor pancreatic islets in a way that evades the immune system to enable insulin secretion for at least 6 months.
Are Post-Meal Insulin Surges Beneficial? - Medscape
Jan 5, 2024 · Rapid surges in insulin following a meal are associated with favorable long-term cardiometabolic benefits, including improvements in beta cell function and a lower risk for the …
What Else Can GLP-1 Drugs Do for Your Patients? - Medscape
Apr 7, 2025 · Glycemic Control The GLP-1 hormone plays a vital role in the regulation of blood sugar levels. Drugs that mimic its action enhance insulin secretion in a glucose-dependent manner and …
Malnutrition-Related Diabetes Officially Named ‘Type 5’ - Medscape
Apr 11, 2025 · Among the findings were lower total insulin secretion in the “type 5” group than in both the lean group without diabetes and the T2D group, significantly lower endogenous glucose …
Diagnosis and Classification of Diabetes Mellitus - Page 2
Jan 1, 2000 · Definition And Description Of Diabetes Mellitus Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or …
Should Insulin Glargine Be Dosed Once or Twice Daily? - Medscape
Dec 2, 2008 · In type 2 diabetic patients with decreased insulin secretion and insulin resistance, a second injection of insulin glargine might be necessary.
Glucose Toxicity in Beta-Cells - Medscape
Our perspective about glucose toxicity as it pertains to the pancreatic ß-cell is that the characteristic decreases in insulin synthesis and secretion are caused by decreased insulin gene expression.
Diagnosis and Classification of Diabetes Mellitus - Page 3
Jan 1, 2000 · The main features of these changes are as follows: The terms insulin-dependent diabetes mellitus and non-insulin-dependent diabetes mellitus and their acronyms, IDDM and NIDDM, are …
From Lab to Landmark Therapy: Meet the Woman Behind GLP-1
Jul 18, 2025 · Our early clinical studies with Nathan were the first to demonstrate that GLP-1 (7-37) stimulates insulin secretion and lowers blood glucose in people with T2D, establishing its therapeutic …
Metal Ions: The Next Frontier in Diabetes Management? - Medscape
May 15, 2025 · In turn, this increases the demand for insulin, leading to excessive insulin production and secretion and insulin resistance. Toxic Metals Not all metal ions are beneficial to the body.